Assistant-Professor in Biochemistry / HRMS-based Exposomics

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Researcher profiles

Young Researcher (with less than 4 years research experience after PhD)

 Established Researcher (with more than 4 years research experience)

Research Fields 

Biological Sciences 


Environmental Science

Medical Sciences 

Main Activities

  • Research: Assessment of human exposure to environmental contaminants (chemical exposome)

Technological advances in high-resolution mass spectrometry (HRMS), combined with the development of innovative bioinformatics tools, allows to characterize on large scale and without any a priori human exposure to chemical mixtures. These novel approaches based on HRMS, called “non-targeted”, provide a unique opportunity to capture the exposome (i.e. the totality of environmental exposures of an individual in a lifetime), and particularly the chemical exposome.This new paradigm for exposure measurement offers new perspectives in the field of environmental health. The strategy of Irset, and more particularly the 3ERD team (Exposure Assessment and Epidemiological Research on Environment, Reproduction and Development) is to develop new research to better understand the links between environmental chemicals exposures and the occurrence of chronic diseases in large scale epidemiological studies. Irset aims, both at the University of Rennes and at the national (medical research) and European levels, to position this theme as a high priority.Consequently, Irset offers a position of permanent assistant professor position. We are seeking candidates with excellent skills in analytical chemistry (and in particular in LC / GC-HRMS) and/or in bioinformatics (big data analysis) to join the 3ERD team which has already developed projects in this new field of research linked to the chemical exposome.

Successful candidate will have a strong background in analytical metabolomics/exposomics and/or bioinformatics for mining HRMS data. He/she will thus be responsible for developing new analytical and/or bioinformatics methods to conduct projects based on non-targeted HRMS analysis, on a large scale, of biological samples from epidemiological cohorts. These projects will aim to characterize, on a broad spectrum, exposures to mixtures of environmental chemicals and to study the existing associations between these exposures and health outcomes of interest to the host team. Strong interactions are expected with the epidemiologists from the host team but also with other Irset researchers with expertise in toxicology and "omics" sciences. The candidate must demonstrate very good communication skills in English in order to teach in English and to interact regularly with foreign researchers.

Key-words: Biochemistry, Metabolic biochemistry, Omics, bioinformatics

  • Teaching:
  1. Teaching general and analytical biochemistry as well as metabolism (French and English) to undergraduated students. Experience using omics techniques and integrated dimension of biochemistry, as well as research assessment of human exposure to environmental contaminants, especially environmental chemicals, in order to build Master degree teaching in the field. 

Associated Activities

  • N/A

Specific Requirements or Constraints 

  • N/A


  • -

Required Experience

  1.   2 to 4 years,  4 to 10 years,  >10 years 
  2. Fields: Biochemistry, Metabolic biochemistry, Omics, bioinformatics

Required Education Level or Diploma

  • PhD

Required Languages

  • French, English

Hosting Unit Code UR1  Name University of Rennes 1, Faculty of Life and environmental sciences, and the associated Inserm research institute « Institut de recherche en santé, environnement et travail (Irset) / Research Institute for Environmental and Occupational Health - U1085 Director Claire Piquet-Pellorce Composition 2800 students in life and environmental sciences, 120 lecturers, 20 persons for administrative and technical assistance. The research institute includes close to 300 persons, 10 research teams, and 1 technology platform Address Teaching on Beaulieu campus, research on Villejean Campus | F-35000 RENNES Website Contract Type permanent contract Duration permanent Salary According to experience Envisaged 
Start Date September 1, 2022        


For more details and to apply, please refer to Galaxie website:

Applicants should confirm their application by sending their CV to: Yves Le Dréan ( and Arthur David (

Deadline for application: 31 March 2022

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Job details

Assistant-Professor in Biochemistry / HRMS-based Exposomics
9 Avenue du Professeur Léon Bernard Rennes, France
Application deadline
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About the employer

The Irset work in a number of complementary areas such as molecular biology, genomics, bioinformatics, analytical chemistry, toxicology and epidemi...

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