University of Oulu

Doctoral Researcher in Intervertebral Disc Experimental Therapeutics

2022-09-30
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About the employer

University of Oulu is an international science university which creates innovation for the future and knowledge through multidisciplinary research ...

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We at the University of Oulu work as part of the international science community to produce new scientific information and science-based solutions. We are committed to educating future pioneers to build a more sustainable, intelligent and humane world. Creating new knowledge, taking responsibility and succeeding together are values that build a strong foundation for all our actions. We offer a working environment where individuals can cultivate their skills and develop professionally. Our university's world-leading specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.

 

We are now looking for a dedicated and promising

Doctoral Researcher

to join the group of Professor Ali Mobasheri to work on an interdisciplinary project focused on the formulation and testing of experimental therapeutics for the treatment of intervertebral disc degeneration and low back pain, including nanotechnology, senolytics, and cell-based gene therapy. This project will establish a translational large animal model of intervertebral disc degeneration to test novel therapeutics for back pain. The main objective of the project is to specifically target the cartilaginous components in the discovertebral junction. The research project will be carried out under the FIBROBESITY programme – targeting obesity-related fibrotic pathologies. More information at https://www.oulu.fi/en/fibrohealth-combatting-fibrosis-chronic-diseases.

The faculty and the research group

Applications are invited for a Doctoral Researcher in the research group of Ali Mobasheri in the Research Unit of Medical Imaging, Physics and Technology within the Faculty of Medicine. The new research group led by Ali Mobasheri will develop and test new targeted injectable biological and cellular therapies for osteoarthritis and intervertebral disc degeneration. The new team is funded by the Academy of Finland and the FIBROBESITY programme at the University of Oulu. The aim of this project is to address the translational gap in the treatment of painful intervertebral disc degeneration by testing experimental therapeutics that specifically target the cartilage endplate, a highly specialized tissue that is crucial for intervertebral disc nutrition and homeostasis. The successful candidate will use a translational large animal model of intervertebral disc degeneration for testing novel experimental therapeutics.

The Research Unit of Medical Imaging, Physics and Technology and the Faculty of Medicine provide an excellent environment for doing cutting-edge research in musculoskeletal sciences, supported by state-of-the-art facilities located at Oulu, Finland with many collaborations and links abroad, particularly in USA, Canada and South Korea.

Qualification requirements

You must possess a Master´s degree in any of the following disciplines: molecular biology, biochemistry, physiology, translational research, anatomy, pharmacology, biomedical sciences, pathology or musculoskeletal sciences. We would also welcome applications from graduates in clinical medicine and veterinary science. Experience of working with mammalian cell and tissue culture would be considered an advantage. You should have a strong interest in learning cutting-edge methods related to translational, molecular and biochemical research. Previous demonstrated research experience in molecular biology and basic bioinformatics skills would be considered a significant advantage.

You should be able to work independently as well as in a group with a drive to excel in research. Fluency in both written and spoken English is required. Most importantly, we expect you to have a strong motivation to conduct high-level research in musculoskeletal research and molecular medicine. See also the education requirements for Doctoral degree studies given by the University of Oulu graduate school, UniOGS.

What we offer

We offer a research environment with excellent technological facilities and a motivating and supporting international community at the Faculty of Medicine, University of Oulu. We can also offer access to state-of-the-art facilities located at Oulu, Finland as well as across Europe for doing cutting edge research in musculoskeletal research and precision medicine. You will be working in a highly talented research group supported by an excellent network of collaborators in Finland and abroad. University´s wide variety of support services are at your disposal, allowing you to focus on research work. The position is fixed-term 4-year starting in October 2022 or soon thereafter. A trial period of 6 months is applied in the position.

Salary

The salary will be based on the demand levels 2-4 of the salary system of Finnish Universities for teaching and research personnel. In addition, a salary component based on personal work performance will be paid (maximum of 50% of the job-specific component). Starting gross salary will be approx. 2400-2500 € per month (before taxes).

How to apply

Applications, together with all relevant enclosures, should be submitted using the electronic application form by 30 September 2022 (23:59 Finnish local time). The application should be written in English and include the following:

1) A motivation letter (max. 2 pages) summarizing the applicant’s educational background, professional experience and describing why the applicant is interested in this position.

2) A complete Curriculum vitae (max. 4 pages) preferably in accordance with the guidelines of the Finnish Advisory Board on Research Integrity http://www.tenk.fi/en/template-researchers-curriculum-vitae including a list of publications (if available) and contact information of two referees who may be asked to give a statement on the candidate.

3) Certificates/Diplomas: Scanned copy of the original master’s degree certificate and transcript of records and, when necessary, official translations to Finnish or English.

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top candidates will be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

Further information

For further information, informal enquires can be sent to Ali Mobasheri by E-mail (ali.mobasheri@oulu.fi) with a subject line “Regarding doctoral researcher position in Intervertebral Disc Experimental Therapeutics”.

About Oulu, Finland

Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. The Oulu region is home to over 200 000 people making it the largest urban centre in the Nordics and one of the fastest growing regions in northern Finland. Oulu is a combination of beautiful, northern nature, vivid cultural life and modern technology. Oulu is also known for its highly educated people and friendly, easy-going atmosphere. Living in Oulu is easy – everything is only max. 20 minutes away! Find out more about Oulu: https://www.oulu.fi/university/living-in-oulu

Modified 18.8.2022: Degree requirements specified.

Job details

Title
Doctoral Researcher in Intervertebral Disc Experimental Therapeutics
Location
Pentti Kaiteran katu 1 Oulu, Finland
Published
2022-08-16
Application deadline
2022-09-30
Job type
PhD
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