In vivo Pharmacology Research Scientist/Senior Scientist, Orion Corporation

Description of position

The Antibody-Drug Conjugates Research Team is seeking a talented and highly motivated in vivo pharmacology Research Scientist/Senior Scientist. The successful candidate will possess a PhD or MSc and extensive hands-on in vivo work experience in academic or industry settings. We are looking for someone with a proven track record of planning and executing in vivo studies, excellent teamwork skills, and a profound understanding of cancer biology. The chosen candidate will have the opportunity to work collaboratively with a diverse team of researchers and assistants to drive the advancement of groundbreaking Antibody-Drug Conjugates (ADCs) from the conceptual stage to the clinical candidate phase. This role provides an exciting opportunity to apply expertise in cancer research and contribute to the development of potentially life-saving therapies.

Key responsibilities 

• Independently design, perform/coordinate, and analyze results of efficacy and PK/PD in vivo studies aimed at the discovery of antibody-drug conjugates.
• Develop and optimize experimental protocols and methodologies.
• Build strong partnerships with key stakeholders to understand scientific challenges and project needs, and actively facilitate the execution of in vivo studies.
• Support in-vivo needs across the Oncology research organization.
• Present research findings to project teams and management and prepare technical reports.
• Work with external academic, biotechnology, and contract research organizations to advance our projects.
• Commit to scientific rigor, high data quality, and careful documentation.

This permanent position is located in Turku, Finland, and reports directly to the Head of the Antibody-Drug Conjugates Team.  

Description of unit 

The Antibody-Drug Conjugates Team is one of three scientific units in Oncology Research, a part of Orion's RnD Organization. The team is focused on discovering therapeutic targets and actively developing ADCs by utilizing a broad panel of biophysical, biochemical, cellular, and in vivo methods. We aim to develop cutting-edge ADC therapies that can transform cancer patients' lives.

We offer 

We offer the opportunity to work alongside talented and experienced scientists and assistants across Orion’s R&D, where you'll be part of an exciting pipeline in an enthusiastic working environment that allows you to leverage your strengths to enhance your competence and build your career. You’ll also have the unique chance to innovate and contribute to future therapies for patients. Our excellent working atmosphere is built on mutual trust, continuous development, and a strong appreciation of colleagues. Please visit our website to find further information about Orion as an employer https://www.orion.fi/en/careers/orion-as-an-employer/.

Requirements

To be successful in this role, the candidate must have the demonstrated knowledge, skills, and abilities in the following: 

• MSc/PhD in cancer biology, pharmacology, or relevant with at least 4 years of hands-on in vivo work experience in academic or industry settings.
• Authorized competencies to work with laboratory animals.
• Demonstrated hands-on experience in planning and executing in vivo pharmacology studies, including diverse mouse models and routes of drug administration, monitoring techniques, and sample collection.
• Strong knowledge of tumor biology, supported by a publication record.
• Understanding of pharmacology and PK/PD principles.
• Good understanding of the Animals (Scientific Procedures) Act.
• Ability to work independently and collaboratively within multidisciplinary research teams, and experience in coordinating research assistant work.
• Excellent problem-solving, critical thinking, communication, and presentation skills.
• Highly organized with documentation of experimental plans, timelines, and reports.

Additional information

Are you interested in this opportunity? Please send your application with the latest CV, cover letter, and salary request in English by September 18th, 2024. We will start reviewing applications during the application period.

For additional details, do not hesitate to contact Dr Marcin Chrusciel, Head of Antibody Drug Conjugates Team tel. +358 509667861 on any of the following times (Finnish Time): 6th of September 15:00-16:00 and 13th of September 15:00-16:00.

#LI-ORION

Approved medical examination which also includes drug testing is required prior to the employment. We will also carry out a security clearance prior to the employment for the selected person.

Orion Corporation operates in more than 30 countries, where we Orionees, 3600 in total, work in all kinds of positions. Among us there are Research Scientists, Laboratory Technicians, Engineers and IT Specialists as well as people working in Production, just to mention some examples. We offer diverse and responsible jobs to our personnel in a truly multi-disciplinary work environment. We encourage people to develop their competences and offer opportunities to affect the job description and creating their own career path at Orion. We are searching for top talents who are ready to share our passion for the work that we do.