Lorraine Université d’Excellence (LUE) Program is inviting applications for a post-doctoral position (100%, 12 months) to develop a conceptual framework for measurement of flare in chronic inflammatory diseases, within the “GEENAGE” IMPACT project (Functional Genomics, Epigenomics and Environmental interplay to IMPACT the understanding, diagnosis and management of healthy and pathological AGEing”).
The concept of flare is regularly used in inflammatory diseases. Flare are generally thought of as a paroxysmal increase in the usual symptoms of the disease, but there is not always a formal and consensual definition for each inflammatory disease.
Recent researches have focused on the problem of measuring relapse in chronic inflammatory diseases, with the aim to have a better representation of patients' experiences beyond the average state usually measured in inflammatory disease.
The APEMAC research unit, developing a research theme on “Concepts and methods in measurement of perceived health”, has several ongoing studies on tools to measure relapse in various chronic diseases: rheumatoid arthritis, osteoarthritis, chronic inflammatory bowel disease. The objective of these three studies is to produce a diagnostic and measurement tool for the flares in the form of a self-questionnaire, based on the analysis of patients' speeches. It should be noted that these studies did not postulate an a priori definition of flares; on the contrary, the flare object is reconstructed from the verbatim. In fact, for these studies, the flares are defined by the items and domains that make up the measuring instruments produced.
This bottom-up approach has the advantage of remaining as close as possible to the patient's experience; the disadvantage is that it does not lead to a concept that can be manipulated and extended to other inflammatory diseases.
Objective and organization of the research:
The general objective of this post-doctoral position is to look at whether the idea of a universal concept of relapse for the different existing inflammatory diseases makes sense, and if so, to produce a complete, consensual framework and usable definition of relapse in inflammatory diseases.
The first practical objective of the position will be to complete (and publish) a systematic literature review on the concept of relapse and its measurement in the various identifiable inflammatory chronic diseases.
The second practical objective of the position is to propose a conceptual basis for a flare based on the results of the systematic literature review as well as the evidence already collected within the studies conducted by APEMAC. Once the concept has been developed, the fellow will organize a consultation of international experts (e.g. Delphi method) in order to refine the concept and confirm its consensual nature. The whole process should be documented in order to be published.
Major publications of the unit in this topic:
TERMS AND TENURE
These 12 months post-doctoral position will be based in Nancy, at APEMAC unit (EA 4360).
The duration cannot exceed 12 months.
The target start date for the position is March 2020, with some flexibility on the exact start date.
HOW TO APPLY
Applicants are requested to submit the following materials:
• A cover letter applying for the position
• Full CV and list of publications
• Academic transcripts (unofficial versions are fine)
Applicants will be interviewed by an ad hoc commission [Day to define at the start of January 2020].
Applications are only accepted through email to the responsible of the research program: Dr. Francis Guillemin & Dr. Jonathan Epstein.
All documents must be sent to mailto: email@example.com / firstname.lastname@example.org
Deadline for application is February 27, 2020.
Nancy, Lorraine, France at APEMAC Research unit (EA 4360), Université de Lorraine.Continue reading
|Title||Postdoctoral Fellowship - Development of a conceptual framework for measurement of flare in chronic inflammatory diseases|
|Employer||Lorraine Université d'Excellence (LUE)|
|Job location||34 Cours Léopold, 54000 Nancy|
|Published||January 20, 2020|
|Application deadline||February 27, 2020|
|Job types||Postdoc  |
|Fields||Gerontology,   Pathology,   Genetics,   Epidemiology,   Health Psychology,   Public Health  |