Postdoc (m/f/x) – YAP / TAZ in Cancer Mechanotransduction

The Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena is a federal and state government-funded research institute and member of the Leibniz Association (Leibniz-Gemeinschaft). FLI’s internationally visible and highly competitive research is focused on understanding the mechanisms of aging and associated age-related diseases. Scientists from over 40 countries are currently investigating the molecular mechanisms of aging and the occurrence of age-related diseases. Our aim is to create the basis for new approaches in medicine as a way to improve the health of the elderly (www.leibniz-fli.de).

The Research Group led by Dr. Björn von Eyß at FLI is looking for a highly motivated and talented postdoctoral researcher to join a DFG-funded research project:

POSTDOC (M/F/X)

Job-ID: 25/03
Application by February 28, 2025

Research focus of the lab:

The von Eyß Research Group studies the Hippo pathway and its impact on organ regeneration, cancer, and aging. This signaling pathway has two effector proteins: the transcriptional coactivators YAP and TAZ. The research group focuses on different aspects of the biology of YAP / TAZ. The goal is to identify novel signaling pathways that control YAP / TAZ activity.

Your tasks:

The DFG-funded research project aims to explore the “decoding of the cytoplasmic role of YAP / TAZ in cancer mechanotransduction”

• Investigation of the role of YAP / TAZ in mechanotransduction
• Identification of cytoplasmic signalling cues that are influenced by YAP / TAZ in a new mouse model
• Characterization of the mechanisms by which YAP / TAZ are regulated in cytoplasmic signalling pathways

Your qualifications:

• PhD in biology, life science, biomedicine, or in an equivalent discipline
• Genuine interest in pursuing an independent academic career
• Experience in molecular biology, biochemistry, and cell biology techniques
• Experience in basic bioinformatics (Linux, R) would be desirable
• FELASA-equivalent certification and experience in the planning, execution, and documentation of animal experiments is a plus but not a prerequisite
• Excellent spoken and written English and German

We offer:

• You will become part of a world-leading research institute dedicated to the biology of aging and have the opportunity to join a very well-equipped Lab with an international team and the focus on stem cell biology
• Access to multiple state-of-the-art facilities; our work is embedded in the Beutenberg Campus, an interdisciplinary base for innovative research
• A position integrated in the FLI Postdoc Network; the Network promotes interdisciplinary collaborations involving clinician scientists, basic scientists, and bioinformaticians and supports career development and postdoctoral training courses
• The contract conditions and the salary will be according to the collective labor agreement for public service employees of the federal states of Germany (E 13 TV-L)
• Flexible working time, a family-friendly working environment that provides a healthy work-life balance, company health management, including support for child care solutions, and dual careeroptions
• We provide support with various qualification and further training opportunities and use of the Haufe learning platform with numerous different online courses

Application:

Please apply online through the FLI application portal by February 28, 2025.

FLI is proud to be an equal opportunity employer and promotes diversity. It aims to increase the proportion of underrepresented groups in case of equal suitability. All qualified persons, regardless of race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status, or other classification protected by law will receive consideration for employment.