KU Leuven

PhD Position on epigenetic ecotoxicology

2024-09-15 (Europe/Brussels)
Save job

About the employer

KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

Visit the employer page

The Division of Ecology, Evolution and Biodiversity Conservation is part of the Biology Department at KU Leuven. We aim to improve our understanding of the eco-evolutionary dynamics of natural populations in relation to their local environment. We combine fieldwork with genetic data analysis and state-of-the-art modelling techniques to answer eco-evolutionary questions such as "how do pollutants impact molecular diversity and evolutionary potential?"
More information ? See https://bio.kuleuven.be/research
Website unit

Project

Pollutants such as bisphenol, PFAS and pesticides are posing an increasing threat to environmental health, and likely contribute to ongoing biodiversity loss due to their massive and widespread presence even in remote areas.  Understanding and forecasting the effects of chemical pollution on biodiversity are among the major challenges of our time.  A particularly underexplored effects of pollutants on biodiversity is how they may impact mutation and evolution.   The BISGO project aims to study how bisphenol A  (BPA), a widely used plastic additive , and a potential safe and sustainable BPA alternative (Bisguiacol, BG), drive epigenetic variation across the Daphnia genome, and how this epigenetic variation in turn affects mutation rates.  This study will be among the first to reveal the effects of pollutants on mutation rates in ecological systems.  Importantly, the development of BG is testimony to Belgium's commitment towards a more circular economy.

The successful PhD candidate will be among the first to join a team of researchers from KU Leuven, Ghent University and Sciensano, addressing how epigenetic variation and environmental stressors interact to shape natural mutation rate variation.  This position, under the supervision of Prof. Hanne De Kort, will focus on the genotoxicity of BPA and of BGs in Dapnia magna, an ideal ecology study system for sequence-evolve-resequence experiments.  Such experiments will reveal epigentic and genetic signals specifically associated with pollutants, and how these signals alter evolution in response to heat stress.  In combination, the impact of pollution will be studied on multi-trophic systems with algae and Daphnia, to verify whether conclusions hold in more complex ecological systems.

Profile

  • You hold a MSc degree in a relevant field (Biology, Bioscience Engineering, Environmental Sciences or related fields) or you will have obtained it by the time you start working
  • You can demonstrate excellent study results, with at least a distinction degree
  • You have passion for nature and biodiversity
  • You have a background in evolutionary biology and/or genetics
  • You have a background in programming languages such as R or python
  • You are fluent in English, both written and oral
  • You are willing to collaborate and be a team player with good communications skills

Offer

  • A full-time doctoral fellowship (4 years)
  • Tentative starting date : November 2024
  • The successful candidate will be based at the division Ecology, Evolution and Biodiversity Conservation in Leuven (Belgium)
  • Your monthly scholarship amount is calculated according to the scholarship amounts for doctoral scholarship holders on the pay scales for assistants
  • You will receive ecocheques, a bicycle and a bicycle allowance or a full reimbursement of public transport costs for commuting.  See : https://admin.kuleuven.be/mykuleuven/en/theme/hr-wellbeing/salary-benefits-insurances for full benefits including holidays and bonuses.  
  • Collaboration in a young and dynamic international scientific team.  Life-work balance is important for us

Interested?

For more information please contact Prof. dr. Hanne De Kort, tel.: +32 16 37 38 25, mail: hanne.dekort@kuleuven.be or Mrs. Conny Coeckelberghs, tel.: +32 16 32 37 17, mail: conny.coeckelberghs@kuleuven.be.

KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.

Job details

Title
PhD Position on epigenetic ecotoxicology
Employer
Location
Oude Markt 13 Leuven, Belgium
Published
2024-08-02
Application deadline
2024-09-15 23:59 (Europe/Brussels)
2024-09-15 23:59 (CET)
Job type
PhD
Save job

More jobs from this employer