KU Leuven

PhD position: metabolic reprogramming in critical illness

2024-07-25 (Europe/Brussels)
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KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

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The selected candidate will conduct translational PhD research under the supervision of Prof. Lies Langouche, Prof. Michael Casaer and Prof. Jan Gunst. You will join the Intensive Care Medicine Research Group, part of the department of Cellular and Molecular Medicine at the University of Leuven (KU Leuven, Belgium). We are a multidisciplinary, translational basic/clinical research team that combines a research laboratory with a large intensive care unit (ICU). This unique combination allows effective cross-talk between knowledge generated from patient studies and from animal and molecular studies in the laboratory.
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Our research focuses on critical illness, what can be defined as any life-threatening condition for which the body requires intensive medical care to prevent death. One of the hallmarks of critical illness is the development of a hypercatabolic response which cannot be counteracted by nutrition alone. This project wants to unravel the observed metabolic dysregulation and identify how nutrition can play either a detrimental or beneficial role in the recovery process of critical illness. We will address our questions in a clinically relevant mouse model of intensive-care-supported critical illness and translate if possible to the human patient in retrospective and prospective studies. 

Keywords: Critical illness, sepsis, metabolism, nutrition


  • We are looking for a highly motivated, enthusiastic, critical, and creative person with a master degree or equivalent in a relevant field, such as Medicine, Biomedical Sciences, Bioscience Engineering, Biomedical Engineering, Biochemistry, Biology (or will obtain this degree in 2024)
  • Good oral and written communication skills
  • Enjoy working both independently and in a team
  • Fluency in English


  • We offer a doctoral position for 1 year in an interdisciplinary environment.  After a positive evaluation, the position is prolonged with 3 years
  • You will work in a translational multidisciplinary research team that is internationally recognized as the expert in research integrating Intensive Care Medicine and Endocrinology/Metabolism/Nutrition
  • You will have access to state-of-the-art research facilities and will be registered in a specific program of the doctoral school


For more information please contact Prof. dr. Lies Langouche, tel.: +32 16 33 05 24, mail: lies.langouche@kuleuven.be

KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.

Job details

PhD position: metabolic reprogramming in critical illness
Oude Markt 13 Leuven, Belgium
Application deadline
2024-07-25 23:59 (Europe/Brussels)
2024-07-25 23:59 (CET)
Job type
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About the employer

KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

Visit the employer page