The Biotechnology and Bioengineering group directed by Prof. Dr Martin Fussenegger at the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel is recruiting PhD students and Postdocs for research projects in the field of Synthetic Biology-inspired human diabetes therapies.

The D-BSSE is the first truly interdisciplinary research department of the Swiss Federal Institute of Technology, the ETH Zurich where theory, experimental biology and engineering groups team up to foster advances in Systems Biology, Biotechnology and Synthetic Biology. With its headquarters and laboratories in Basel, Switzerland, the D-BSSE is situated in the heart of the Bio valley, a tri-national region hosting 40% of the global life science industry including several pharma giants, providing a unique environment for high-leverage translational research.

Our group uses state-of-the-art Synthetic Biology principles to engineer human cells and develop cell-based therapies for the treatment of cancer as well as metabolic, neurodegenerative, autoimmune and infectious diseases. Please consult our webpage and published work for further information.

The project will combine basic and translational research to develop novel synthetic biology-inspired therapies for diabetes. Rational programming of the behaviour of human cells will shape future biomedical applications. This may include the design of novel biosensors, gene switches and genetic closed-loop circuits, or to design of programmable cellular implantable devices.

ETH Zurich is a family-friendly employer with excellent working conditions. You can look forward to an exciting working environment, cultural diversity and attractive offers and benefits.

You are exceptionally motivated to bridge basic and translational research in cell biology and synthetic biology. Strong skills in standard molecular and cell biology techniques and the cultivation and engineering of human pluripotent stem cells and mammalian cell lines are a prerequisite. Hands-on experience in pancreatic differentiation, culture and engineering of human primary cells and mouse experiments are also desirable. We expect a strong publication record as well as the ambition to foster start-up activities.

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.

We look forward to receiving your online application including:

• CV
• full study record
• publication list
• a motivation letter
• two letters of recommendation

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered. For additional questions please contact Professor Martin Fussenegger by mail (martin.fussenegger@bsse.ethz.ch).